Novel Use of Proton Magnetic Resonance Spectroscopy (1HMRS) to Non-Invasively Assess Placental Metabolism

Novel Use of Proton Magnetic Resonance Spectroscopy (1HMRS) to Non-Invasively Assess Placental Metabolism

BACKGROUND Placental insufficiency is a major cause of antepartum stillbirth and fetal growth restriction (FGR). In affected pregnancies, delivery is expedited when the risks of ongoing pregnancy outweigh those of prematurity. Current tests are unable to assess placental function and determine optimal timing for delivery. An accurate, non-invasive test that clearly defines the failing placenta ...

Assessment of Cerebellar Metabolites Levels in Athletes Compared to Non-Athlete by Proton Magnetic Resonance Spectroscopy

Background: Adaptability to exercise training can increase the plasticity of the brain, and whether this can be due to a beneficial change in the neurometabolites, is uncertain. The purpose of this study was to evaluate basal metabolic concentrations of cerebellum, including N-acetyl aspartate (NAA) and Cholin(Cho) in athletes and compare them with non-athlete subjects. Materials and Methods: I...

Proton Nuclear Magnetic Resonance Spectroscopy

Brain Proton Magnetic Resonance Spectroscopy

Magnetic resonance (MR) spectroscopy is an analytical method used in chemistry that enables the identification and quantification of metabolites in samples. It differs from conventionalMR imaging in that spectra provide physiologic and chemical information instead of anatomy. MR spectroscopy and MR imaging have their origin in nuclear magnetic resonance (NMR). NMR was first described in 1946 si...

Brain proton magnetic resonance spectroscopy of alcohol use disorders.

This chapter critically reviews brain proton magnetic resonance spectroscopy ((1)H MRS) studies performed since 1994 in individuals with alcohol use disorders (AUD). We describe the neurochemicals that can be measured in vivo at the most common magnetic field strengths, summarize our knowledge about their general brain functions, and briefly explain some basic human (1)H MRS methods. Both cross...